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1-BOC-Piperazine: The Modular Building Block Behin
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yatsi
12 posts
Aug 25, 2025
9:14 PM
At its core, 1 boc piperazine is a piperazine molecule modified by adding a BOC group (tert-butoxycarbonyl) to one of its two nitrogen atoms. Piperazine itself is a six-membered ring containing two nitrogen atoms in opposite positions. By attaching a BOC group to one nitrogen, chemists temporarily "block" that site, allowing reactions to occur selectively at the other nitrogen.


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