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Member's Message > What is the mechanism of action of Vidalista?
What is the mechanism of action of Vidalista?
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Costtalee
55 posts
May 09, 2024
11:27 PM
Vidalista is a brand name for the generic drug Tadalafil, which belongs to a class of medications called phosphodiesterase type 5 (PDE5) inhibitors. Its mechanism of action involves inhibiting the enzyme PDE5, which is responsible for the degradation of cyclic guanosine monophosphate (cGMP) in the smooth muscle cells of the corpus cavernosum in the penis.

When a man is sexually stimulated, nitric oxide (NO) is released into the erectile tissue of the penis. Vidalista stimulates the enzyme guanylate cyclase, resulting in increased levels of cGMP, which causes relaxation of smooth muscle cells and increased blood flow into the penis. This increased blood flow leads to an erection.

PDE5 normally breaks down cGMP, thus regulating the extent of smooth muscle relaxation and erection. By inhibiting PDE5, Vidalista/Tadalafil prolongs the action of cGMP, resulting in sustained relaxation of smooth muscles and prolonged erection. It's important to note that sexual stimulation is still required for the medication to be effective; it doesn't cause spontaneous erections.


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